Max International: Leading the Way in Glutathione Research
The Need for Glutathione
Glutathione is one of the most important detoxifying agents in the body. It mops up damaging free radicals and reactive oxygen species, protecting the DNA, mitochondria, and other important cellular components. Glutathione is not obtained from the diet but it is instead manufactured in the body from three amino acids that are obtained from the diet (glycine, glutamic acid, and cysteine). Glycine and glutamic acid are abundantly available in foods. The sulfur compound derived from cysteine is essential for glutathione's activity. Unfortunately, cysteine is found in only limited quantities in meat and eggs, and is not found in significant amounts in most plant-based foods.
Individuals subjected to trauma, stress, athletic over-training, and disease are often found to have low levels of glutathione in their bodies, suggesting that the normal dietary intake of cysteine is insufficient to produce enough glutathione during times of increased need. Increasing vitamin D levels in the body seems to stimulate the body to produce more glutathione. S-Adenyl-adenosylmethionine (SAMe) supplementation can also increase glutathione levels. However, in the absence of sufficient raw material (cysteine), the body can only synthesize so much glutathione.
Glutathione cannot be absorbed through the digestive tract, so the only way to boost levels of it in the body is to boost intake of cysteine. Until recently, the only supplementary source of cysteine was N-acetyl cysteine (NAC). NAC can cause a number of side effects, such as allergic reactions, nausea, vomiting, bronchospasms, and pulmonary arterial hypertension. These side effects limit its use as an oral supplement. However, Max International has developed a breakthrough dietary source of cysteine: RiboCeine™. RiboCeine contains cysteine bound to ribose, a sugar molecule that is an essential building block of ATP, the body's source of energy. RiboCeine has none of the disadvantages of NAC and is an effective source of cysteine to allow the body to produce sufficient glutathione to meet the body's needs.
The Vital Role of Glutathione
Glutathione is found in all cells, but it is found in particularly high concentrations in the liver, where it plays an important role in detoxification of the body. In addition to directly removing free radicals and reactive oxygen species, glutathione is essential for maintaining vitamins C and E in their active forms. Glutathione also plays an important role in regulating the nitric oxide cycle, in repairing DNA, in synthesizing proteins, and in transporting and regulating enzymes. Glutathione has an essential role in iron metabolism.
Animals genetically engineered to be unable to produce any glutathione die before birth. Animals engineered to produce only low amounts of glutathione are highly susceptible to any kind of stress or toxic insult and tend to die young. In scientific studies, intravenous administration of glutathione to people has been shown to be able to reverse many of the symptoms of ateriosclerosis. It has also been shown to be able to protect neurons against death after exposure to stress and toxins, an effect that may help prevent Alzheimer's and Parkinson's disease from developing. Intravenous infusion of glutathione has been shown to boost athletic performance. However, daily intravenous infusions of glutathione is not a feasible way to increase glutathione levels in athletes or in the general population.
As an oral supplement that can increase glutathione levels, RiboCeine has been extensively studied. The results of these studies have been published in over 20 peer-reviewed scientific studies. Studies in mice have demonstrated that administration of RiboCeine rapidly increased the amount of glutathione in all tissues. The level of glutathione 16 hours after administration of RiboCeine was elevated 1.5 fold in the liver, 1.8 fold in the heart, and 2.5 fold in the muscles. Other studies have shown that RiboCeine is capable of protecting the liver from overdoses of drugs and help protect the body against the damaging effects of chemotherapy and radiation exposure. In a mouse model of irritable bowel disease, RiboCeine was able to accelerate healing of the colonic lesions. RiboCeine has even been shown to protect against common signs of aging such as hearing loss and cataract formation.
Max International offers RiboCeine as a key component of several products. One key product is Cellgevity, a supplement that contains RiboCeine and 12 other ingredients that act to protect and support the body. Cellgevity has been specially formulated to contain no banned or controlled substances so professional athletes and individuals subjected to regular drug testing can use it to protect their bodies from stress and aging with confidence. Cellgevity is easy to take as two capsules twice a day. In addition to RiboCeine, Cellgevity contains turmeric, resveratrol, quercetin, grape seed extract, black pepper extract, aloe, milk thistle, alpha lipoic acid, broccoli seed extract, vitamin C, selenomethionine, and cordyceps.
Other Products from Max International
For individuals who don't want or can't take a combination of extracts, RiboCeine is available as a pure substance under the name MaxONE. It provides a potent dose of RiboCeine and nothing but RiboCeine to protect your body against stress and toxins. RiboCeine is also available in MaxATP, a targeted formula that boosts energy while protecting the body.
The Man Behind the Science
Dr. Herbert Nagasawa is "the father of RiboCeine." He's a fully qualified organic chemist and biochemist. He has been a full professor of Medicinal Chemistry at the V.A.'s Medical Center in Minneapolis since 1973.